Breaking News, Collaborations & Alliances

AZ, Heptares in GPCR Pact

STaR technology to advance AZ candidates

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By: Tim Wright

Editor-in-Chief, Contract Pharma

AstraZeneca and Heptares Therapeutics have entered a four-year collaboration focused on the potential discovery and development of new medicines targeting G-protein coupled receptors (GPCRs). GPCRs are among the largest and most important family of proteins found in the human body, yet they become highly unstable when removed from their natural membrane-bound environments. This instability has prevented pharmaceutical researchers from understanding GPCR structures and hampered efforts to desi...

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